Abstract
In this tutorial review, which should be of general interest to synthetic organic chemists at large, recent progress in the total synthesis of the tetrahydroisoquinoline antitumor antibiotics cyanocycline A, naphthyridinomycin, bioxalomycin α2, and lemonomycin is highlighted in detail and some biological background information is given as well. Preparations of truncated derivatives and uncompleted synthetic approaches are also described. The literature coverage includes the newest research results through the year 2008. © 2008 The Royal Society of Chemistry.
Originalsprache | Englisch |
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Seiten (von - bis) | 2676-2690 |
Seitenumfang | 15 |
Fachzeitschrift | Chem. Soc. Rev. |
Jahrgang | 37 |
Ausgabenummer | 12 |
DOIs | |
Publikationsstatus | Veröffentlicht - 1 Dez. 2008 |
Extern publiziert | Ja |
Forschungsfelder
- Alkaloide
- Gesamtsynthese
- Stereoselektive Synthese
- Biologische Aktivität
IMC Forschungsschwerpunkte
- Materials science
ÖFOS 2012 - Österreichischen Systematik der Wissenschaftszweige
- 104015 Organische Chemie
- 104013 Naturstoffchemie