Synthesis of the C6-C14 Fragment of Euphosalicin

C. Aichinger; J. Mulzer; U. Rinner

doi:10.1055/s-0034-1380422

Synthesis of the C6-C14 Fragment of Euphosalicin

C. Aichinger, J. Mulzer, U. Rinner

University of Vienna

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

Abstract

The synthesis of the C6-C14 fragment of euphosalicin, a highly oxygenated modified jatrophane diterpene, is described. Key steps in the preparation of this versatile intermediate are an Ireland-Claisen rearrangement and a Shibasaki direct asymmetric aldol reaction.

Originalsprache	Englisch
Aufsatznummer	st-2015-b0256-l
Seiten (von - bis)	1852-1856
Seitenumfang	5
Fachzeitschrift	Synlett
Jahrgang	26
Ausgabenummer	13
DOIs	https://doi.org/10.1055/s-0034-1380422
Publikationsstatus	Veröffentlicht - 19 Juni 2015
Extern publiziert	Ja

Forschungsfelder

Gesamtsynthese
Terpene
Euphorbiaceae Diterpene
Stereoselektive Synthese

IMC Forschungsschwerpunkte

Materials science

ÖFOS 2012 - Österreichischen Systematik der Wissenschaftszweige

104015 Organische Chemie

UN SDGs

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10.1055/s-0034-1380422

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title = "Synthesis of the C6-C14 Fragment of Euphosalicin",

abstract = "The synthesis of the C6-C14 fragment of euphosalicin, a highly oxygenated modified jatrophane diterpene, is described. Key steps in the preparation of this versatile intermediate are an Ireland-Claisen rearrangement and a Shibasaki direct asymmetric aldol reaction.",

keywords = "aldol reaction, hydrostannation, natural products, rearrangement, total synthesis, diterpene, euphosalicin, unclassified drug, Article, Claisen rearrangement, drug synthesis, Ireland Claisen rearrangement, Shibasaki direct asymmetric aldol reaction",

author = "C. Aichinger and J. Mulzer and U. Rinner",

note = "Publisher Copyright: {\textcopyright} Georg Thieme Verlag Stuttgart · New York.",

year = "2015",

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doi = "10.1055/s-0034-1380422",

language = "English",

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T1 - Synthesis of the C6-C14 Fragment of Euphosalicin

AU - Aichinger, C.

AU - Mulzer, J.

AU - Rinner, U.

N1 - Publisher Copyright: © Georg Thieme Verlag Stuttgart · New York.

PY - 2015/6/19

Y1 - 2015/6/19

N2 - The synthesis of the C6-C14 fragment of euphosalicin, a highly oxygenated modified jatrophane diterpene, is described. Key steps in the preparation of this versatile intermediate are an Ireland-Claisen rearrangement and a Shibasaki direct asymmetric aldol reaction.

AB - The synthesis of the C6-C14 fragment of euphosalicin, a highly oxygenated modified jatrophane diterpene, is described. Key steps in the preparation of this versatile intermediate are an Ireland-Claisen rearrangement and a Shibasaki direct asymmetric aldol reaction.

KW - aldol reaction

KW - hydrostannation

KW - natural products

KW - rearrangement

KW - total synthesis

KW - diterpene

KW - euphosalicin

KW - unclassified drug

KW - Article

KW - Claisen rearrangement

KW - drug synthesis

KW - Ireland Claisen rearrangement

KW - Shibasaki direct asymmetric aldol reaction

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DO - 10.1055/s-0034-1380422

M3 - Article

SN - 0936-5214

VL - 26

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EP - 1856

JO - Synlett

JF - Synlett

IS - 13

M1 - st-2015-b0256-l

ER -

Synthesis of the C6-C14 Fragment of Euphosalicin

Abstract

Forschungsfelder

IMC Forschungsschwerpunkte

ÖFOS 2012 - Österreichischen Systematik der Wissenschaftszweige

UN SDGs

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