Synthetic studies towards an advanced precursor of the jatrophane diterpene Pl-4: Synthesis (Germany)

R. Fürst; C. Lentsch; U. Rinner

doi:10.1055/s-0033-1338565

Synthetic studies towards an advanced precursor of the jatrophane diterpene Pl-4: Synthesis (Germany)

R. Fürst, C. Lentsch, U. Rinner

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

Abstract

Jatrophane diterpenes, isolated from members of the Euphorbiaceae plant family, constitute a class of biologically and structurally intriguing natural products. Herein, different strategies for the preparation of an advanced intermediate towards the total synthesis of the jatrophane diterpene Pl-4 are described. Key strategies for the elaboration of the jatrophane precursors include hydrometalation and radical reactions.

Originalsprache	Englisch
Aufsatznummer	SS-2013-T0694-OP
Seiten (von - bis)	357-367
Seitenumfang	11
Fachzeitschrift	Synthesis
Jahrgang	46
Ausgabenummer	3
DOIs	https://doi.org/10.1055/s-0033-1338565
Publikationsstatus	Veröffentlicht - 27 Nov. 2013
Extern publiziert	Ja

Forschungsfelder

Gesamtsynthese
Terpene
Euphorbiaceae Diterpene
Stereoselektive Synthese

IMC Forschungsschwerpunkte

Materials science

ÖFOS 2012 - Österreichischen Systematik der Wissenschaftszweige

104008 Katalyse
104015 Organische Chemie
104013 Naturstoffchemie

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10.1055/s-0033-1338565

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abstract = "Jatrophane diterpenes, isolated from members of the Euphorbiaceae plant family, constitute a class of biologically and structurally intriguing natural products. Herein, different strategies for the preparation of an advanced intermediate towards the total synthesis of the jatrophane diterpene Pl-4 are described. Key strategies for the elaboration of the jatrophane precursors include hydrometalation and radical reactions.",

keywords = "Euphorbiaceae, hydrometalation, jatrophane diterpene, Reformatsky reaction, samarium diiodide, Reaction kinetics, diterpene, jatrophane diterpene Pl 4, unclassified drug, Diterpenes, Hydrometalation, Samarium diiodide, article, chemical reaction, cyclization, hydrometalation reaction, oxygenation, radical reaction, stereochemistry, synthesis, Olefins",

author = "R. F{\"u}rst and C. Lentsch and U. Rinner",

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T2 - Synthesis (Germany)

AU - Fürst, R.

AU - Lentsch, C.

AU - Rinner, U.

N1 - Export Date: 13 June 2023; Cited By: 5; Correspondence Address: U. Rinner; Institute of Organic Chemistry, University of Vienna, 1090 Vienna, Währinger Straße 38, Austria; email: [email protected]; CODEN: SYNTB

PY - 2013/11/27

Y1 - 2013/11/27

N2 - Jatrophane diterpenes, isolated from members of the Euphorbiaceae plant family, constitute a class of biologically and structurally intriguing natural products. Herein, different strategies for the preparation of an advanced intermediate towards the total synthesis of the jatrophane diterpene Pl-4 are described. Key strategies for the elaboration of the jatrophane precursors include hydrometalation and radical reactions.

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KW - Reformatsky reaction

KW - samarium diiodide

KW - Reaction kinetics

KW - diterpene

KW - jatrophane diterpene Pl 4

KW - unclassified drug

KW - Diterpenes

KW - Hydrometalation

KW - Samarium diiodide

KW - article

KW - chemical reaction

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KW - hydrometalation reaction

KW - oxygenation

KW - radical reaction

KW - stereochemistry

KW - synthesis

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Synthetic studies towards an advanced precursor of the jatrophane diterpene Pl-4: Synthesis (Germany)

Abstract

Forschungsfelder

IMC Forschungsschwerpunkte

ÖFOS 2012 - Österreichischen Systematik der Wissenschaftszweige

Zugriff auf Dokument

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