Projects per year
Organisation profile
Organisation profile
The Institute Krems Bioanalytics is the contract research institute of the IMC Krems University of Applied Sciences, which has been offering state-of-the-art bioanalytical services in the fields of immunology, hematology and oncology since 2014.
We have a long-standing expertise in the development and validation of customised and GxP-compliant analytical assays for large molecules and vaccines. With our customised analytical methods, we accompany the different development phases of a drug under strict quality-assured specifications. In addition, the Institute Krems Bioanalytics develops complex cell-based assays for drug efficacy testing or biopotency characterisation for lot releases.
Our current research focuses on the molecular characterisation of the human immune response using mass spectrometry. In addition, we are dedicated to the development of novel approaches to assess the immunogenicity of biomolecules and vaccines and cell-based assays for drug discovery.
The Institute Krems Bioanalytics is located at the Technology and Research Center in Krems, one of the technology-oriented business clusters in Austria. The Biotech Area Krems encompasses three universities and numerous companies specialising in biomedical sciences.
The institute's mission is to be a comprehensive provider of bioanalytical services. It develops state-of-the-art and GxP-compliant technologies for the analysis of samples, generates reliable scientific data, operates in full compliance with regulatory requirements and establishes strategic partnerships in innovative research areas.
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Collaborations and top research areas from the last five years
Profiles
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Peter Allacher
- Institute Krems Bioanalytics - Head of Operations / Institute Krems Bioanalytics
Person: Lecturer/Researcher
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Florian Astelbauer
- Institute Krems Bioanalytics - Projectmanagement / Institute Krems Bioanalytics
Person: Research Assistent
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Stefanie Brandstetter
- Institute Krems Bioanalytics - PhD Student in Biomedical Mass Spectrometry / Institute Krems Bioanalytics
Person: Research Assistent
Projects
- 2 Finished
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Advanced personalized diagnostics to overcome severe side effects of protein therapeutics
Eger, A. (CoI), Lubich, C. (CoI), Allacher, P. (PI) & Paul, H. (CoI)
Gesellschaft für Forschungsförderung Niederösterreich
24/07/17 → 10/08/23
Project: Research
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Metabolic plasma profiling of the metabolic syndrome and cancer cachexia
Jacobi, N. (CoI) & Eger, A. (PI)
Gesellschaft für Forschungsförderung Niederösterreich
18/01/16 → 24/03/21
Project: Research
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Bridging basic science and applied diagnostics: Comprehensive viral diagnostics enabled by graphene-based electronic biosensor technology advancements
Herdina, A. N., Bozdogan, A., Aspermair, P., Dostalek, J., Klausberger, M., Lingg, N., Cserjan-Puschmann, M., Aguilar, P. P., Auer, S., Demirtas, H., Andersson, J., Lötsch, F., Holzer, B., Steinrigl, A., Thalhammer, F., Schellnegger, J., Breuer, M., Knoll, W. & Strassl, R., 21 Sept 2024, (E-pub ahead of print) In: Biosensors and Bioelectronics. 267, p. 116807 116807.Research output: Contribution to journal › Article › peer-review
Open Access -
Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation
Gassner, T., Chittilappilly, C., Pirich, T., Neuditschko, B., Hackner, K., Lind, J., Aksoy, O., Graichen, U., Klee, S., Herzog, F., Wiesner, C., Errhalt, P., Pecherstorfer, M., Podar, K. & Vallet, S., 3 May 2024, In: Journal for ImmunoTherapy of Cancer. 12, 5, e008669.Research output: Contribution to journal › Article › peer-review
Open Access -
The spectrum of neutralizing and non-neutralizing anti-FVIII antibodies in a nationwide cohort of 788 persons with hemophilia A
Oomen, I., Verhagen, M., Miranda, M., Allacher, P., Beckers, E. A. M., Blijlevens, N. M. A., van der Bom, J. G., Coppens, M., Driessens, M., Eikenboom, J. C. J., Fijnvandraat, K., Hassan, S., van Heerde, W. L., Hooimeijer, H. L., Jansen, J. H., Kaijen, P., Leebeek, F. W. G., Meijer, D., Paul, H. & Rijpma, S. R. & 6 others, , 22 Feb 2024, In: Frontiers in Immunology. 15, p. 1355813 1355813.Research output: Contribution to journal › Article › peer-review
Open Access