Research output per year
Research output per year
- 1 - 50 out of 66 results
Search results
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2024
Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation
Gassner, T., Chittilappilly, C., Pirich, T., Neuditschko, B., Hackner, K., Lind, J., Aksoy, O., Graichen, U., Klee, S., Herzog, F., Wiesner, C., Errhalt, P., Pecherstorfer, M., Podar, K. & Vallet, S., 3 May 2024, In: Journal for ImmunoTherapy of Cancer. 12, 5, e008669.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Beyond Pattern Recognition: TLR2 Promotes Chemotaxis, Cell Adhesion, and Migration in THP-1 Cells
Colleselli, K., Ebeyer-Masotta, M., Neuditschko, B., Stierschneider, A., Pollhammer, C., Potocnjak, M., Hundsberger, H., Herzog, F. & Wiesner, C., 19 May 2023, In: Cells. 12, 10, 1425.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative and Temporal Characterization of LPS and Blue-Light-Induced TLR4 Signal Transduction and Gene Expression in Optogenetically Manipulated Endothelial Cells
Stierschneider, A., Neuditschko, B., Colleselli, K., Hundsberger, H., Herzog, F. & Wiesner, C., 22 Feb 2023, In: Cells. 12, 5, 697.Research output: Contribution to journal › Article › peer-review
Open Access -
Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes
Dereli, I., Telychko, V., Papanikos, F., Raveendran, K., Xu, J., Boekhout, M., Stanzione, M., Neuditschko, B., Imjeti, N. S., Selezneva, E., Tuncay, H., Demir, S., Giannattasio, T., Gentzel, M., Bondarieva, A., Stevense, M., Barchi, M., Schnittger, A., Weir, J. R. & Herzog, F. & 2 others, , 27 Nov 2023, In: Nature Communications. 15, 1, p. 2941 2941.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1
Woike, S., Eustermann, S., Jung, J., Wenzl, S. J., Hagemann, G., Bartho, J., Lammens, K., Butryn, A., Herzog, F. & Hopfner, K.-P., May 2023, In: Nature Structural and Molecular Biology. 30, 5, p. 640-649 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Integrated multiomic approach for identification of novel immunotherapeutic targets in AML
Köhnke, T., Liu, X., Haubner, S., Bücklein, V., Hänel, G., Krupka, C., Solis-Mezarino, V., Herzog, F. & Subklewe, M., Dec 2022, In: Biomarker Research. 10, 1, p. 43 43.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes
Kratzat, H., Mackens-Kiani, T., Ameismeier, M., Potocnjak, M., Cheng, J., Dacheux, E., Namane, A., Berninghausen, O., Herzog, F., Fromont-Racine, M., Becker, T. & Beckmann, R., 4 Jan 2021, In: EMBO Journal. 40, 1, p. e105179 e105179.Research output: Contribution to journal › Article › peer-review
Open Access -
Phospho-regulated Bim1/EB1 interactions trigger Dam1c ring assembly at the budding yeast outer kinetochore
Dudziak, A., Engelhard, L., Bourque, C., Klink, B. U., Rombaut, P., Kornakov, N., Jänen, K., Herzog, F., Gatsogiannis, C. & Westermann, S., 15 Sept 2021, In: EMBO Journal. 40, 18, p. e108004 e108004.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast
Killinger, K., Böhm, M., Steinbach, P., Hagemann, G., Blüggel, M., Jänen, K., Hohoff, S., Bayer, P., Herzog, F. & Westermann, S., 15 Jul 2020, In: EMBO Journal. 39, 14, p. e102938 e102938.Research output: Contribution to journal › Article › peer-review
Open Access -
C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast
Ghodgaonkar-Steger, M., Potocnjak, M., Zimniak, T., Fischböck-Halwachs, J., Solis-Mezarino, V., Singh, S., Speljko, T., Hagemann, G., Drexler, D. J., Witte, G. & Herzog, F., 29 Sept 2020, In: Cell Reports. 32, 13, p. 108190 108190.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
A conserved filamentous assembly underlies the structure of the meiotic chromosome axis
West, A. M. V., Rosenberg, S. C., Ur, S. N., Lehmer, M. K., Ye, Q., Hagemann, G., Caballero, I., Usón, I., Macqueen, A. J., Herzog, F. & Corbett, K. D., 18 Jan 2019, In: eLife. 8, e40372.Research output: Contribution to journal › Article › peer-review
Open Access -
First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study
Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P., Bernfur, K., Borchers, C., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T., Degliesposti, G., Dong, M. Q., Edinger, N., Emanuelsson, C. & Gay, M. & 54 others, , 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 6953-6961 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fuzzy Interactions Form and Shape the Histone Transport Complex
Ivic, N., Potocnjak, M., Solis-Mezarino, V., Herzog, F., Bilokapic, S. & Halic, M., 21 Mar 2019, In: Molecular Cell. 73, 6, p. 1191-1203.e6Research output: Contribution to journal › Article › peer-review
Open Access -
The COMA complex interacts with Cse4 and positions Sli15/ipl1 at the budding yeast inner kinetochore
Fischböck-Halwachs, J., Singh, S., Potocnjak, M., Hagemann, G., Solis-Mezarino, V., Woike, S., Ghodgaonkar-Steger, M., Weissmann, F., Gallego, L. D., Rojas, J., Andreani, J., Köhler, A. & Herzog, F., 21 May 2019, In: eLife. 8, e42879.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
CompleXView: A server for the interpretation of protein abundance and connectivity information to identify protein complexes
Solis-Mezarino, V. & Herzog, F., 3 Jul 2017, In: Nucleic Acids Research. 45, Webserver-Issue, p. W276-W284 9 p., Webserver-Issue.Research output: Contribution to journal › Article › peer-review
Open Access -
Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading
Böttcher, R. T., Veelders, M., Rombaut, P., Faix, J., Theodosiou, M., Stradal, T. E., Rottner, K., Zent, R., Herzog, F. & Fässler, R., 6 Nov 2017, In: Journal of Cell Biology. 216, 11, p. 3785-3798 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of the RZZ complex and molecular basis of its interaction with Spindly
Mosalaganti, S., Keller, J., Altenfeld, A., Winzker, M., Rombaut, P., Saur, M., Petrovic, A., Wehenke, A., Wohlgemuth, S., Müller, F., Maffini, S., Bange, T., Herzog, F., Waldmann, H., Raunser, S. & Musacchio, A., 3 Apr 2017, In: Journal of Cell Biology. 216, 4, p. 961-981 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding
Ye, Q., Kim, D. H., Dereli, I., Rosenberg, S. C., Hagemann, G., Herzog, F., Tóth, A., Cleveland, D. W. & Corbett, K. D., 15 Aug 2017, In: EMBO Journal. 36, 16, p. 2419-2434 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Architecture and RNA binding of the human negative elongation factor
Vos, S. M., Pöllmann, D., Caizzi, L., Hofmann, K. B., Rombaut, P., Zimniak, T., Herzog, F. & Cramer, P., 10 Jun 2016, In: eLife. 5, JUNE2016, e14981.Research output: Contribution to journal › Article › peer-review
Open Access -
CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore
Pekgöz Altunkaya, G., Malvezzi, F., Demianova, Z., Zimniak, T., Litos, G., Weissmann, F., Mechtler, K., Herzog, F. & Westermann, S., 12 Sept 2016, In: Current Biology. 26, 17, p. 2370-2378 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Determination of local chromatin composition by CasID
Schmidtmann, E., Anton, T., Rombaut, P., Herzog, F. & Leonhardt, H., 2 Sept 2016, In: Nucleus. 7, 5, p. 476-484 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Insights from biochemical reconstitution into the architecture of human kinetochores
Weir, J. R., Faesen, A. C., Klare, K., Petrovic, A., Basilico, F., Fischböck, J., Pentakota, S., Keller, J., Pesenti, M. E., Pan, D., Vogt, D., Wohlgemuth, S., Herzog, F. & Musacchio, A., 8 Sept 2016, In: Nature. 537, 7619, p. 249-253 5 p.Research output: Contribution to journal › Article › peer-review
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Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster
Liu, Y., Petrovic, A., Rombaut, P., Mosalaganti, S., Keller, J., Raunser, S., Herzog, F. & Musacchio, A., Feb 2016, In: Open Biology. 6, 2, p. 150236 150236.Research output: Contribution to journal › Article › peer-review
Open Access -
Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress
Poli, J., Gerhold, C. B., Tosi, A., Hustedt, N., Seeber, A., Sack, R., Herzog, F., Pasero, P., Shimada, K., Hopfner, K. P. & Gasser, S. M., 1 Feb 2016, In: Genes and Development. 30, 3, p. 337-354 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
Friese, A., Faesen, A. C., Huis, P. J., Fischböck, J., Prumbaum, D., Petrovic, A., Raunser, S., Herzog, F. & Musacchio, A., 20 Apr 2016, In: Nature Communications. 7, p. 11407 11407.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural and functional insights into the fly microRNA biogenesis factor Loquacious
Jakob, L., Treiber, T., Treiber, N., Gust, A., Kramm, K., Hansen, K., Stotz, M., Wankerl, L., Herzog, F., Hannus, S., Grohmann, D. & Meister, G., Mar 2016, In: RNA. 22, 3, p. 383-396 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural basis for the disaggregase activity and regulation of Hsp104
Heuck, A., Schitter-Sollner, S., Józef Suskiewicz, M., Kurzbauer, R., Kley, J., Schleiffer, A., Rombaut, P., Herzog, F. & Clausen, T., 30 Nov 2016, In: eLife. 5, NOVEMBER2016, e21516.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1
Gallego, L. D., Steger, M. G., Polyansky, A. A., Schubert, T., Zagrovic, B., Zheng, N., Clausen, T., Herzog, F. & Köhler, A., 20 Sept 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 38, p. 10553-10558 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
Petrovic, A., Keller, J., Liu, Y., Overlack, K., John, J., Dimitrova, Y. N., Jenni, S., van Gerwen, S., Stege, P., Wohlgemuth, S., Rombaut, P., Herzog, F., Harrison, S. C., Vetter, I. R. & Musacchio, A., 3 Nov 2016, In: Cell. 167, 4, p. 1028-1040.e15Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of transcribing mammalian RNA polymerase II
Bernecky, C., Herzog, F., Baumeister, W., Plitzko, J. M. & Cramer, P., 28 Jan 2016, In: Nature. 529, 7587, p. 551-554 4 p.Research output: Contribution to journal › Article › peer-review
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Topology and structure of an engineered human cohesin complex bound to Pds5B
Hons, M. T., Huis Int Veld, P. J., Kaesler, J., Rombaut, P., Schleiffer, A., Herzog, F., Stark, H. & Peters, J. M., 23 Aug 2016, In: Nature Communications. 7, p. 12523 12523.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
A modular open platform for systematic functional studies under physiological conditions
Mulholland, C. B., Smets, M., Schmidtmann, E., Leidescher, S., Markaki, Y., Hofweber, M., Qin, W., Manzo, M., Kremmer, E., Thanisch, K., Bauer, C., Rombaut, P., Herzog, F., Leonhardt, H. & Bultmann, S., 30 Sept 2015, In: Nucleic Acids Research. 43, 17, p. e112 e112.Research output: Contribution to journal › Article › peer-review
Open Access -
Architecture of the RNA polymerase II-Mediator core initiation complex
Plaschka, C., Larivière, L., Wenzeck, L., Seizl, M., Hemann, M., Tegunov, D., Petrotchenko, E. V., Borchers, C. H., Baumeister, W., Herzog, F., Villa, E. & Cramer, P., 19 Feb 2015, In: Nature. 518, 7539, p. 376-380 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores
Klare, K., Weir, J. R., Basilico, F., Zimniak, T., Massimiliano, L., Ludwigs, N., Herzog, F. & Musacchio, A., 6 Jul 2015, In: Journal of Cell Biology. 210, 1, p. 11-22 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Basis of Transcription-Coupled Pre-mRNA Capping
Martinez-Rucobo, F. W., Kohler, R., van de Waterbeemd, M., Heck, A. J. R., Hemann, M., Herzog, F., Stark, H. & Cramer, P., 18 Jun 2015, In: Molecular Cell. 58, 6, p. 1079-1089 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone
Kock, M., Nunes, M. M., Hemann, M., Kube, S., Jürgen Dohmen, R., Herzog, F., Ramos, P. C. & Wendler, P., 22 Jan 2015, In: Nature Communications. 6, p. 6123 6123.Research output: Contribution to journal › Article › peer-review
Open Access -
XVis: A web server for the schematic visualization and interpretation of crosslink-derived spatial restraints
Grimm, M., Zimniak, T., Kahraman, A. & Herzog, F., 1 Jul 2015, In: Nucleic Acids Research. 43, W1, p. W362-W369 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A
Hornung, P., Troc, P., Malvezzi, F., Maier, M., Demianova, Z., Zimniak, T., Litos, G., Lampert, F., Schleiffer, A., Brunner, M., Mechtler, K., Herzog, F., Marlovits, T. C. & Westermann, S., 18 Aug 2014, In: Journal of Cell Biology. 206, 4, p. 509-524 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterization of a DNA exit gate in the human cohesin ring
Huis In't Veld, P. J., Herzog, F., Ladurner, R., Davidson, I. F., Piric, S., Kreidl, E., Bhaskara, V., Aebersold, R. & Peters, J. M., 21 Nov 2014, In: Science. 346, 6212, p. 968-972 5 p.Research output: Contribution to journal › Article › peer-review
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Conserved architecture of the core RNA polymerase II initiation complex
Mühlbacher, W., Sainsbury, S., Hemann, M., Hantsche, M., Neyer, S., Herzog, F. & Cramer, P., 10 Jul 2014, In: Nature Communications. 5, p. 4310 4310.Research output: Contribution to journal › Article › peer-review
Open Access -
Measuring spatial restraints on native protein complexes using isotope-tagged chemical cross-linking and mass spectrometry
Herzog, F., 2014, Structural Genomics: General Applications. Humana Press Inc., Vol. 1091. p. 259-273 15 p. (Methods in Molecular Biology; vol. 1091).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Modulation of the chromatin phosphoproteome by the haspin protein kinase
Maiolica, A., De Medina-Redondo, M., Schoof, E. M., Chaikuad, A., Villa, F., Gatti, M., Jeganathan, S., Lou, H. J., Novy, K., Hauri, S., Toprak, U. H., Herzog, F., Meraldi, P., Penengo, L., Turk, B. E., Knapp, S., Linding, R. & Aebersoldab, R., Jul 2014, In: Molecular and Cellular Proteomics. 13, 7, p. 1724-1740 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of the VipA/B type VI secretion complex suggests a contraction-state-specific recycling mechanism
Kube, S., Kapitein, N., Zimniak, T., Herzog, F., Mogk, A. & Wendler, P., 10 Jul 2014, In: Cell Reports. 8, 1, p. 20-30 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The pseudo GTPase CENP-M drives human kinetochore assembly
Basilico, F., Maffini, S., Weir, J. R., Prumbaum, D., Rojas, A. M., Zimniak, T., De Antoni, A., Jeganathan, S., Voss, B., Van Gerwen, S., Krenn, V., Massimiliano, L., Valencia, A., Vetter, I. R., Herzog, F., Raunser, S., Pasqualato, S. & Musacchio, A., 8 Jul 2014, In: eLife. 2014, 3, p. e02978 e02978.Research output: Contribution to journal › Article › peer-review
Open Access -
2013
Cross-Link Guided Molecular Modeling with ROSETTA
Kahraman, A., Herzog, F., Leitner, A., Rosenberger, G., Aebersold, R. & Malmström, L., 16 Sept 2013, In: PLoS ONE. 8, 9, p. e73411 e73411.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural features of Argonaute-GW182 protein interactions
Pfaff, J., Hennig, J., Herzog, F., Aebersold, R., Sattler, M., Niessing, D. & Meister, G., 1 Oct 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. E3770-E3779Research output: Contribution to journal › Article › peer-review
Open Access -
Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex
Tosi, A., Haas, C., Herzog, F., Gilmozzi, A., Berninghausen, O., Ungewickell, C., Gerhold, C. B., Lakomek, K., Aebersold, R., Beckmann, R. & Hopfner, K. P., 12 Sept 2013, In: Cell. 154, 6, p. 1207-19 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2012
Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage
Jennebach, S., Herzog, F., Aebersold, R. & Cramer, P., Jul 2012, In: Nucleic Acids Research. 40, 12, p. 5591-5601 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography
Leitner, A., Reischl, R., Walzthoeni, T., Herzog, F., Bohn, S., Förster, F. & Aebersold, R., Mar 2012, In: Molecular and Cellular Proteomics. 11, 3, p. M111.014126Research output: Contribution to journal › Article › peer-review
Open Access -
False discovery rate estimation for cross-linked peptides identified by mass spectrometry
Walzthoeni, T., Claassen, M., Leitner, A., Herzog, F., Bohn, S., Förster, F., Beck, M. & Aebersold, R., Sept 2012, In: Nature Methods. 9, 9, p. 901-903 3 p.Research output: Contribution to journal › Article › peer-review