Abstract
In this tutorial review, which should be of general interest to synthetic organic chemists at large, recent progress in the total synthesis of the tetrahydroisoquinoline antitumor antibiotics cyanocycline A, naphthyridinomycin, bioxalomycin α2, and lemonomycin is highlighted in detail and some biological background information is given as well. Preparations of truncated derivatives and uncompleted synthetic approaches are also described. The literature coverage includes the newest research results through the year 2008. © 2008 The Royal Society of Chemistry.
Original language | English |
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Pages (from-to) | 2676-2690 |
Number of pages | 15 |
Journal | Chem. Soc. Rev. |
Volume | 37 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1 Dec 2008 |
Externally published | Yes |
Research fields
- Alkaloids
- Total Synthesis
- Stereoselective synthesis
- Biological activity
IMC Research Focuses
- Materials science
ÖFOS 2012 - Austrian Fields of Study
- 104015 Organic chemistry
- 104013 Natural product chemistry